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Patients with complex partial seizures of temporal lobe origin may experience behavioural disorders like depressive, anxiety-related or schizophrenic-like symptoms between seizures, i.e. interictally. The neural mechanisms underlying these enduring interictal disorders remain to be investigated. The aim of the present study was to examine the behavioural consequences of kindling of the basolateral...
It has recently been shown for the tree shrew that after 10days of psychosocial stress, when the central nervous noradrenergic and adrenergic systems are highly activated, α 2 -adrenoceptors are down-regulated in brain regions which are involved in the regulation of autonomic functions [Flugge G. et al. (1992) Brain Res. 597, 131-137]. The present study demonstrates the dynamic changes occurring...
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