The National Institute on Aging and Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer’s Disease The Working Group participants included: Drs. M. Ball, Oregon Health Sciences University, Portland, OR; H. Braak, J. W. Goethe University, Frankfurt, Germany; P. Coleman, University of Rochester Medical Center, Rochester, NY; D. Dickson, Albert Einstein College of Medicine, Bronx, NY; C. Duyckaerts, Hopital De La Salpetriere, Paris, France; P. Gambetti, University Hospital of Cleveland, Cleveland, OH; L. Hansen, University of San Diego, La Jolla, CA; B. Hyman, Massachusetts General Hospital, Boston, MA; K. Jellinger, Ludwig Boltzman Institute, Vienna, Austria; W. Markesbery, University of Kentucky, Lexington, KY; D. Perl, Mt. Sinai School of Medicine, New York, NY; J. Powers, University of Rochester Medical Center, Rochester, NY; J. Price, Washington University School of Medicine, St. Louis, MO; J. Q. Trojanowski, University of Pennsylvania School of Medicine, Philadelphia, PA and H. Wisniewski, Institute for Basic Research in Developmental Disabilities, Staten Island, NY. Drs. C. Phelps and Z. Khachaturian represented the National Institute on Aging and the Ronald and Nancy Reagan Research Institute of the Alzheimer’s Association, respectively. The meeting was chaired by Dr. J. Q. Trojanowski on Nov. 13–14, 1996 at the National Institutes of Health in Bethesda, MD, and Drs. B. Hyman and J. Q. Trojanowski cochaired and led the concluding deliberations to formulate the consensus criteria summarized here. Dr. John Q. Trojanowski, Working Group Chair, Department of Pathology and Laboratory Medicine, Univ. of Pennsylvania School of Medicine, HUP, Maloney Bldg., Room A009, Philadelphia, PA, USA 19104-4283
This report summarizes the consensus recommendations of a panel of neuropathologists from the United States and Europe to improve the postmortem diagnostic criteria for Alzheimer s disease. The recommendations followed from a two-day workshop sponsored by the National Institute on Aging (NIA) and the Ronald and Nancy Reagan Institute of the Alzheimer s Association to reassess the original NIA criteria...