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Depolarizing GABA A receptor-mediated currents are contributed by HCO 3− efflux, and play a role in initiating ictal-like epileptiform events in several cortical structures supporting the view that GABA A receptor signaling actively participates to epileptiform synchronization. We employed here field potential recordings to analyze the effects of the carbonic anhydrase...
The medial prefrontal cortex (mPFC) has been implicated in multiple disorders characterized by clear sex differences, including schizophrenia, attention deficit hyperactivity disorder, post-traumatic stress disorder, depression, and drug addiction. These sex differences likely represent underlying differences in connectivity and/or the balance of neuronal excitability within the mPFC. Recently, we...
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