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Synthesis of 3-aryloxy-2-oxindole derivatives from 3-hydroxy-2-oxindoles and aryl boronic acids through copper(II)-promoted reaction is achieved. This reaction provides an efficient protocol for the coupling between aryl boronic acid and tertiary aliphatic alcohol, opening a new avenue to format corresponding 3-phenyl-3-aryloxy-2-oxindole core, which has potentially value in the field of life-science.
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