A microsurgery assisting system for minimally invasive neurosurgery has been developed. Three sets of micromanipulators and a rigid endoscope are integrated together in a thin tubular insertion part. Each manipulator has three degrees of freedom and controlled through the control levers on the console. The manipulator has tubular structure, which allows a thin operating device to travel through it. It has been verified that the device can take up in-vivo tissue and the laser knife works well with the manipulator.