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Multiple dose pharmacokinetics of artemether and dihydroartemisinin were investigated in chinese patients treated for malaria. They received over 2 days either 4x80 mg artemether orally (n=48) or 4x80-480 mg co-artemether (n=40), a combination of artemether and lumefantrine (benflumetol). Lag time=0.48 h (mean), C max after first dose=157 ng/ml, t max =1.73 h and...
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