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Given the increased level of adrenergic stimulation in burn patients, it would be expected that they would experience an increased incidence of cardiac arrhythmias and other cardiac events. We performed a retrospective chart review of 56 acute burn patients matched by age, length of hospital stay, and sex to 56 trauma patients, all of whom had been continuously monitored electrocardiographically....
Most studies investigating the pathophysiological processes taking place inside an experimental burn wound use in vitro techniques, which only allow for fragmented measurements of the actual and complex processes occurring inside a burn wound in vivo. In the present study, which used a recently developed in vivo technique in the rat, a full-thickness burn was induced and resulted in the formation...
In immobilized patients, unrelieved pressure can create decubitus ulcers over bony prominences. Those burn patients who require prolonged bed rest, are prone to the development of such problems. Various methods of reducing pressure on these areas, including frequent turning and the use of air fluidized and low air loss beds, have been adopted to attempt to prevent the development of this complication...
The amelioration of corticosteroid-impairment of healing by a stable gastric pentadecapeptide BPC-157 (GEPPPGKPADDAGLV, M w 1419, currently in early clinical trials for inflammatory bowel disease) was studied in thermally injured mice. Its effects on corticosteroid impaired healing of deep partial skin thickness burns, and burn-gastric lesions were investigated. Male NMRI-Hannover mice (sacrificed...
Objective: To show the effectiveness of an integrated therapeutical approach in a severe case of acute respiratory distress syndrome (ARDS) following burns, inhalation injury with therapy-refractory oxygenation under maximized ventilatory settings, and an overall complicated clinical course. Patient and methods: Case report of a patient with severe inhalation injury and burns in an intensive care...
A case of deep high energy electrical burn of the skull is presented. For assessment of bone regrowth and muscle flap viability after application of latissimus dorsi free flap, combined 99m Tc MDP bone SPECT and 99m Tc sestamibi muscle SPECT scintigraphy were used. Whereas 99m Tc MDP bone SPECT showed absent uptake at the beginning, there was good...
Inhalation of chemical and particulate products of smoke is one of the principal determinant of mortality following burn injury. Inflammatory responses have been implicated in the pathogenesis of lung injury after smoke inhalation. In the current study, we tested the inhibitory effect of Fucoidin on the neutrophil rolling stage of inflammatory response and determined the degree of pulmonary injury...
Objectives: To document and describe the effects of flammable liquid burns in children. To identify the ''at risk'' population in order to tailor a burns prevention programme.Design, patients and setting: Retrospective study with information obtained from the departmental database of children treated at the burns centre at The Royal Children's Hospital, Brisbane between August 1997 and October 2002...
Records of patients presenting to the Emergency Department (ED) of the Prince of Wales Hospital with wax burns during Mid-Autumn festival from 1998 to 2001 were retrieved and analyzed. There were 26 patients in total (21 males, 5 females). Annual attendances from 1998 to 2001 were 11, 7, 4 and 4, respectively. Age ranged from 1 to 33 years (median age: 11.5). Most patients were injured by molten wax...
We reviewed the emergence of 13 cases of multi-resistant Acinetobacter infection in burns patients over a 12-month period. The outbreak was started in a non-burn patient in the intensive care unit (ICU) that spread to burns patients in ICU and then the Burns Unit. The importance of opportunistic infection, potential risk factors, treatment and clinical outcome of Acinetobacter infection in burns patients...
With about 2 million cases of burns in India of which about 90% are superficial and superficial partial thickness burns, burn injuries present a major challenge to the scarce medical resources available. The main requirement in treating these burns is an economical, easy to apply, readily available dressing that will provide good pain relief, protect the wound from infection, promote healing, prevent...
This study was prospectively carried out on 880 acutely burned patients admitted to the Burn Unit of Ain Shams University in Cairo, Egypt, during the period from the 1 May 1995 to the 31 October 2001, with the objective to analyze the epidemiological features of burned patients in our country. The means of age and percentage total body surface area burned (TBSB) were 27.8+/-2.9 years and 32+/-5.7%,...
The susceptibility of thermally injured mice (TI-mice) to murine cytomegalovirus (MCMV) infection is markedly influenced by burn-associated type 2 T cell responses, which are common with severe thermal injuries. In the present study, the effect of soluble IL-4 receptor (sIL-4R) on the skin-graft-associated MCMV infection was investigated. The marked growth of MCMV was demonstrated in the salivary...
This case report describes the successful wound management of a 19-year-old patient with 76% of his body surface burnt. Due to the severity of the burns and the limited availability of native skin, 63% of the body surface were covered with Integra ( R), a dermis equivalent. This material has been developed for the reconstruction of dermal structures and is designed as a bilayer. It consists...
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