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An ultrasensitive and enzyme-free sensing platform was designed for sensitive detection of anterior gradient homolog 2 (AGR2) based on the fluorescence quenching of gold nanoparticles (AuNPs) coupled with hybridization chain reaction (HCR) amplification. To construct the sensor, two fluorophore labeled hairpin probes (HP1 and HP2) that contained the sticky tails were designed, and AGR2 aptamer was...
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