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Angeli's salt (Na 2 N 2 O 3 ) decomposes into nitroxyl (HNO) and nitrite (NO 2- ), compounds of physiological and therapeutic interest for their impact on biological signaling both through nitric oxide and nitric oxide independent pathways. Both nitrite and HNO oxidize oxygenated hemoglobin to methemoglobin. Earlier work has shown that HNO catalyzes the reduction...
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