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The E. coli RecBCD enzyme facilitates the loading of RecA onto single-stranded DNA produced by the combined helicase/nuclease activity of RecBCD. The nuclease domain of RecB protein, RecB nuc , has been previously shown to bind RecA. Surprisingly, RecB nuc also binds to phage and eukaryotic homologs of RecA, leading to the suggestion that RecB nuc interacts with the polymerization...
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