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One enigma in the biology of hyperthermophilic microorganisms, living near or above 100 o C, is how their genomes can be stable and, at the same time, plastic at temperatures above the melting point. The non-specific DNA-binding protein Sso7d of the hyperthermophilic archaeon Sulfolobus solfataricus is known to protect DNA from thermal denaturation. We report here that Sso7d promotes the renaturation...
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