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Considerably high toxicity was detected in marine puffers collected from Masinloc Bay, Philippines. The toxicity was detected in the liver, intestine, muscle and skin. Noteworthy, the specimens, the muscle of which showed high toxicity, appeared in high frequency, indicating that puffers from this area is not safe for human consumption. These puffer specimens contained paralytic shellfish poisoning...
This report describes the preparative scale production of 11-[ 3 H]-tetrodotoxin (TTX) and its evaluation as a substitute for [ 3 H]-saxitoxin (STX) as the radioligand in a receptor binding assay for paralytic shellfish poisoning (PSP) toxins. Restrictions on the world-wide distribution of [ 3 H]-STX imposed by the international Chemical Weapons Convention served as the primary...
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