The gasification of organics in supercritical water is a promising method for the direct production of hydrogen at high pressures, and in order to improve the hydrogen yield or selectivity, activities of various catalysts are evaluated. In this study, hydrogen production from 2-propanol over Ni/Al 2 O 3 and Fe–Cr catalysts was investigated in supercritical water. The experiments were carried out in the temperature range of 400–600°C and in the reaction time range of 10–30s, under a pressure of 25MPa. The hydrogen yields and selectivities of Ni/Al 2 O 3 and Fe–Cr used in this study, and those of Pt/Al 2 O 3 and Ru/Al 2 O 3 used in our previous work were compared. The hydrogen contents of the gaseous products obtained by using Ni/Al 2 O 3 and Fe–Cr were measured as 62mol% and 70mol%, respectively, at low temperatures and reaction times. However, the hydrogen yields remained in low levels when compared with that of Pt/Al 2 O 3 used in previous study. Pt/Al 2 O 3 was established to be the most effective and selective catalyst for hydrogen production. During the catalytic gasification of a 0.5M solution of 2-propanol, hydrogen content up to 96mol% and hydrogen yield of 1.05mol/mol 2-propanol were obtained.