The aim of this study was to evaluate the effect of low frequency ultrasound plus lymphatic drainage on Blood Triglycerides in Cardiac patients (chronic coronary atherosclerosis patients, with high triglycerides and fat mass body composition). Low frequency ultrasound plus lymphatic drainage as a technique could be used as an alternative to conventional exercise and alternative to many obesity surgery as Liposuction surgery and thus provide an opportunity to improve the quality of obese cardiac patient as many obesity surgery have a lot of hazards and sides effect that may affect the patient especially those with cardiac conditions, and that result could be achieved with the usage of LFUS plus LD technique in order to reduce the blood serum triglycerides, fat cells size and even destruction of adiposities with acceptable penetration and get rid of that cells out of the body preventing hazards and complication as thrombosis and many cardiovascular complicated that can be a result of high blood serum triglycerides and high total body fat mass).Forty female patients with age ranges from 40 to 50years were selected from Palestine Hospital, they were chronic atherosclerotic patients and were assigned into 2 groups according to their BMI based on the classification of the world health organization, each patient in the two groups (Group A and Group B) was evaluated before and after 24 sessions treatment program by using the combination of ultrasound and lymphatic drainage machine, the assessment of blood serum triglycerides by UDICHEM-310 ANALYSER have been done before and after the end of 24 sessions and Re-assessment after 2months from the last treatment session. The collected raw data of the current patients were statistically analyzed to evaluate the results of the two groups to investigate the effect of using the combination of ultrasound and lymphatic drainage machine on blood serum triglycerides, the data obtained in the current stud revealed statistical significance changes in blood serum triglycerides, and revealed that, there was a significant improvement (reduction) in the total blood serum triglycerides for the Group A (Class I) and, Group B (Class II ) groups at the three stages of the measurements (Pre, Post, and Post II), and revealed that there was a strong significant correlation between, the reduction of fat mass post-treatment and the reduction of the total body triglycerides (Post II) treatment (two months after the last session). Low frequency ultrasound technique plus lymphatic drainage technique improve blood serum triglycerides of chronic cardiac patients.