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We have previously reported that α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA)-receptor blockade within the rostral ventrolateral medulla (RVLM) attenuates cardiovascular responses and extracellular concentrations of glutamate during mechanical, but not during thermal stimulation [Pharmacol. Res. 43 (2001) 47]. In this study, we examined the role of nitric oxide (NO) within the RVLM...
Inducible nitric oxide (NO) synthase (iNOS) is believed to contribute to the pathogenesis of endotoxin-induced uveitis (EIU). In the present study, we investigated the inhibitory effects of N G -nitro-l-arginine methyl ester (l-NAME), a non-selective NOS inhibitor, and S,S'-1,4-phenylene-bis(1,2-ethanediyl)bis-isothiourea (PBITU), a potent and selective iNOS inhibitor, on intraocular NO production...
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