Coupling of the trisaccharide acceptor 2,4,6-tri-O-acetyl-β-d-glucopyranosyl-(1->3)-[2,3,4,6-tetra-O-benzoyl-β-d- glucopyranosyl-(1->6)]-5-O-acetyl-1,2-O-isopropylidene-α-d-glucofuranose (2) with the trisaccharide donor 2,3,4,6-tetra-O-benzoyl-α-d-annopyranosyl-(1->3)-[2,3,4,6-tetra-O-benzoyl-@ b-d-glucopyranosyl-(1->6)]-2,4-di-O-acetyl-α-d-glucopyranosyl trichloroacetimidate (1) gave an α-linked hexasaccharide 3, while coupling of 2 with the trisaccharide donor 2,3,4,6-tetra-O-benzoyl-α-d-mannopyranosyl-(1->3)-[2,3,4,6-tetra-O-benzoyl- α-d-mannopyranosyl-(1->6)]-2,4-di-O-acetyl-α-d-glucopyranosyl trichloroacetimidate (7) produced α- 8 and β-linked 12 hexasaccharides in a ratio of 3:2. Deprotection of 3, 8, and 12 afforded the analogues of the immunomodulator β-d-Glcp-(1->3)-[β-d-Glcp-(1->6)]-α-d-Glcp-(1->3)-β-d-Glcp-(1->3)-[β-d- Glcp-(1->6)]-d-Glcp (A).