Cholelithiasis is one of the most common surgical diseases associated with aging. Although laparoscopic cholecystectomy (LC) is the best treatment modality for the symptomatic cholelithiasis, its safety in geriatric population is still controversial. The aim was to evaluate the outcomes of LC in geriatric patients, in comparison to youngers.A total of 1298 patients who underwent elective or emergent LC for gallbladder stone were included in this study. Patients were divided into two main groups: Group 1 (18–64 years old) and Group 2 (≥65 years old). The outcomes of LC between the age groups was compared with each other.There were 1027 (79.1%) patients in Group 1 and 271 patients (20.9%) in Group 2. Older age group had higher Charlson comorbidity index (CCI) score (p < 0.001), higher ASA scores (p < 0.001), longer operating time (p = 0.007), and longer hospitalization time (p < 0.001) than youngers. The majority of patients (86%) were discharged within the first two postoperative days. Age ≥65 years (p < 0.001), CCI score (p = 0.004), ASA score (p = 0.024), and postoperative complication (p < 0.001) were independent factors of prolonged hospitalization (≥3 days). Conversion rates were similar between the groups. Presence of acute cholecystitis (p < 0.001) and intraoperative complication (p < 0.001) were found to be independent factors of conversion.This study showed that LC can be safely performed in elderly patients, without any significant increase in perioperative morbidity. Presence of acute cholecystitis is the main factor of conversion in all ages. Therefore, surgeons should be more careful in such patients.