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Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with complex aetiology. Genetic polymorphisms disrupting the functions of genes encoding anti-inflammatory cytokines such as IL1Ra may influence the disease activity and outcome in SLE. In this study, the IL1Ra VNTR polymorphism was tested for its influence on disease susceptibility, clinical and serological phenotypes of SLE in South...
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