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This research studied the anticonvulsant properties of three synthesized isomers of dichloro-substituted phenyl amino propanamides in rodents and determined their effects on votage-gated sodium channels (NaV1.6) stably expressed in Human Embryonic Kidney (HEK Cells 293). 2,3-, 2,5- and 3,4- Dichloro anilines were reacted with acrylamide according to Michael-type addition reaction to obtain their corresponding...
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