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Association study is the method of choice to identify genes involved in complex processes that result from the interaction of environmental and genetic factors. However, because of biases that increase the risk of false positive reports, preliminary positive conclusions have to be reproduced on other populations to be validated as firm conclusions. In 1994, certain alleles of two genes, APOE (Apolipoprotein...
Afin de tester si les mutations responsables du daltonisme sont transmises plus fréquemment par des pères âgés, un recensement exhaustif des naissances dans la région de Namur a permis d’isoler un échantillon de 225 garçons descendant de grands-pères maternels ayant dépassé 45 ans à la naissance de leur fille. L’incidence de daltonisme a été comparée entre ce groupe de cas et trois groupes témoins...
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