Several studies have reported that certain aspects of the household environments are associated with adverse birth outcomes, but associations have been inconsistent. Few of these studies have been conducted in China. During 2011–2012, we conducted a retrospective cross-sectional study and collected 13,335 parents-reported questionnaires for 4–6-year-olds children in Shanghai, China. We investigated associations of household environmental factors (environmental tobacco smoke (ETS), cooking fuel, dampness, pet-keeping, and home renovation) during gestation with preterm birth (PTB, gestational age<37weeks), low birth weight (LBW, birth weight<2500g), term low birth weight (T-LBW, LBW when the gestational age was ≥37weeks), and small for gestational age (SGA, birth weight<10th percentile of birth weight for gestational age). A total of 4.1% children were premature; 2.9% had LBW and 1.6% had T-LBW; 8.1% were SGA. In the multiple logistic regression analyses, home renovation during gestation was associated with PTB (adjusted odds ratio (OR), 95% confidence intervals (CI): 1.68, 1.11–2.54) and LBW (1.64, 0.99–2.72). Paternal smoking was associated with PTB (1.18, 0.98–1.43). No significant associations were found for SGA. Neither household dampness nor cooking fuel were significantly associated with birth outcomes. For boys, paternal smoking was associated with PTB (1.31, 1.02–1.69); home renovation during gestation was associated with PTB (2.14, 1.27–3.61) and LBW (2.19, 1.09–4.43). Among children whose mothers were ≥34-year-olds during gestation, paternal smoking (1.73, 1.04–2.76) and home renovation during gestation (1.80, 1.18–2.76) was associated with PTB. Our findings demonstrate that home renovation and ETS during gestation may be risk factors for adverse birth outcomes. Associations of these factors with adverse birth outcomes appear to be stronger in boys and among mothers older than 34years during gestation. Home renovation and ETS exposure should be avoided during gestation, especially for pregnancies with male fetuses and older pregnant women.