Interest in hydrosulfido (SH) complexes stems from their relevance to metalloenzymes and metal sulfide catalysts for industrial hydrodesulfurization. This review provides an overview of the chemistry of hydrosulfido complexes of transition metals. Synthetic methods of hydrosulfido complexes will first be classified, followed by the description of their spectroscopic properties and structural features. Significant emphasis is also placed on the reactivities of hydrosulfido complexes including nucleophilic reactions, oxidative coupling, and sulfido cluster formation.