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We compared total 25-OH vitamin D status measured by DiaSorin Liaison and tandem mass spectrometry (LC-MS/MS) among patients with high and low 25-OH vitamin D 2 .Total 25-OH vitamin D was measured in plasma containing high (>25nmol/l or >50%, n=26) and low (<2.5nmol/l, n=29) 25-OH vitamin D 2 using DiaSorin Liaison and an LC-MS/MS method using NIST 972-verified calibrators...
Mass spectrometry provides a powerful platform for performing quantitative, multiplexed assays in the clinical laboratory, but at the cost of increased complexity of analysis and quality assurance calculations compared to other methodologies.Here we describe the design and implementation of a software application that performs quality control calculations for a complex, multiplexed, mass spectrometric...
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