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An organic solvent-tolerant Bacillus licheniformis ZSP01 was newly isolated and utilized as a whole-cell biocatalyst for efficient production of skimmin and 6′-succinylskimmin from umbelliferone. Strikingly, the production of skimmin and 6′-succinylskimmin was significantly increased in the reaction media added with 10% dimethylsulfoxide (DMSO), and was separately regulated by adjusting the nitrogen...
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