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A physiologically based toxicokinetic and toxicodynamic (PBTK-TD) model was developed for benzo[a]pyrene (B[a]P) in scallop Chlamys farreri. The PBTK model structure consisted of gill, digestive gland, adductor muscle, hemolymph and other tissues. In TD modeling, aryl hydrocarbon hydroxylase (AHH) activity assay, comet assay, protein carbonyl measurement and lipid peroxidation level determination...
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