In order to supply accurate databases for different practical purposes such as proton beam energy monitoring, 4 8 V radioisotope production, nuclear analytical applications and nuclear wear measurements, we have evaluated the cross-sections of the n a t Ti(p,x) 4 8 V nuclear process up to 50 MeV. Since the preliminary overview of the status of the cross-section data showed that there are discrepancies between the literature results, we performed detailed cross-section measurements up to 18 MeV. The selected literature data and our new experimental values were also compared with the predictions of different model calculations. Recommended cross-sections and thick target yield databases up to 50 MeV were developed for practical applications.