This paper is concerned with the problems of stability analysis and l 2 -gain control for a class of two-dimensional (2D) nonlinear stochastic systems with time-varying delays and actuator saturation. Firstly, a convex hull representation is used to describe the saturation behavior, and a sufficient condition for the existence of mean-square exponential stability of the considered system is derived. Then, a state feedback controller which guarantees the resulting closed-loop system to be mean-square exponentially stable with l 2 -gain performance is proposed, and an optimization procedure to maximize the estimation of domain of attraction is also given. All the obtained results are formulated in a set of linear matrix inequalities (LMIs). A numerical example is given to illustrate the effectiveness of the proposed method.