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This study examined, in young and old (3 and 24month-old, respectively) healthy Wistar rats, the in vivo effect of DHEA (10mg/kg body weight) administered subcutaneously for 5weeks. Reduced (GSH) and oxidized (GSSG) glutathione levels, glucose — 6-phosphate dehydrogenase (G6PDH), glutathione peroxidase (GPx), glutathione-S-transferase (GST) and thioredoxin (Trx) reductase activities, hydrogen peroxide...
Reduced muscle mass and strength are likely fundamental components of frailty. The purpose of this study was to measure daily muscle activity and quiescence in non-frail, pre-frail, and frail older women using portable electromyography (EMG). Thirty-three community-dwelling older Greek women were categorized as non-frail (n=10, 74±4years), pre-frail (n=11, 75±4years), and frail (n=12, 81±6years) based...
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