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We compared the DNA-binding activity of transcription factors and gene expression patterns in BJ human diploid fibroblasts (HDFs) expressing or not telomerase (hTERT) in stress-induced premature senescence (SIPS). Senescent BJ cells were also studied. Hydrogen peroxide (H 2 O 2 )-induced SIPS modulated gene expression in both BJ and hTERT-BJ1 cells. Increased p21 WAF...
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