As of today in Hungary, the live-birth rate is continuously declining, but the number of babies born from out of marriage relationship is increasing. According to the National Statistical Office, the later number represents 28% in 1999. In the past 30 years, we have been engaged in many cases where an adult wants to be informed about his or her ancestry. Out of these plentiful caseloads, we would like to present three interesting cases. Case 1: Identification of two stepbrothers with chromosomal and DNA investigations-without examining the parents. Case 2: Proved family relationship (father-son) with chromosomal translocation studies (22/Y). Case 3: After 55 years, family members were identified (blood groups, anthropology, chromosomes, DNA) of a prisoner of war (POW).