To explore and study the significant value of “Tiānou ( TE 16) five acupoints” in treatment of clinical diseases based on analysis of three cases. Case 1: thyroid enlargement. Acupuncture was conducted at Rényíng ( ST 9), Fútū ( LI 18), Shuľtū ( ST 10) and Qìshè ( ST 11), and combined with Nèiguān ( PC 6). After ten courses of treatment, nodules and calcified lesions shrank. Case 2: hyperplasia of mammary glands. Acupuncture was conducted at bilateral ST 9 and TE 16, and combined with Tàichōng ( LR 3) and Dànzhōng ( CV 17). After eight courses of treatment, the breast lumps disappeared. Case 3: hyperprolactinemia, and amenorrhea for two years. Acupuncture was conducted at bilateral ST 9, TE 16 and Tiānfŭ ( LU 3), and combined with LR 3 and Xiáxī ( GB 43). After eleven courses of treatment, the content of prolactin was normal.