Purpose: It has not been resolved how are the driver's physiocal conditions when driving a car in a highway. Although sleepiness for drivers during driving seems to be one of the important causative factors for car accidents, there are few reports studied on sleepiness for drivers.Method [amp ] Subjects: We recorded sculp EEG, eye movements and mental muscle EMG using multi-purpose EEG apparatus for 15 healthy men with more than 20 years-old ages, in a private car throughout long distance highway drives, at least more than 2 hours in a daytime and also in night time.Results: EEG findings for drivers during long distance highway drivings show initially beta activities. As the time goes on, (1) blinkings of eye-lids increase, (2) diffuse slower alpha activity appears when drivers close their eye lids, (3) continuous theta activities persist, and (4) sometimes sleep spindle appears. These findings are severe when drivers complain of sleepiness, but they are recognized even when drivers do not complain of any sleepiness. On electrical stimulation for drivers, their EEG activities tend to return back to [beta ] activities.Conclusion: It is worth recognizing that drivers can drive a car with sleepiness or even without sleepiness when EEG shows sleep patterns during a long distance highway driving.