No currently available biomaterial exhibits all of the necessary properties for optimum ureteral stenting. This study reports the manufacture and characterisation of interpenetrating polymeric (PU/PMMA) networks (sIPN) which have been designed as ureteral stent biomaterials.PMMA was prepared by mixing methylmethacrylate (MMA; 99.5% w/w) and azobisisobutyronitrile (AIBN; 0.5% w/w). The solution was cast between two glass plates and heated at 60oC for 18h. sIPNs were prepared by immersion of strips of PU into a solution containing MMA and AIBN (99.5:0.5) for the required time period, following which the strips were heated as before. Ultimate tensile strength (TS, MPa), % elongation at break (Elong) and Young's modulus (YM, GPa) were obtained by tensile testing, whereas the Storage modulus (E', GPa) and damping parameter (tan δ) were obtained by Dynamic Mechanical Analysis. Advancing (Adv) and receding (Rec) contact angles of sIPN, PU and PMMA were determined using a Dynamic Contact Analyser at 25oC. The coefficient of variation in all cases was <3% and therefore only mean values are shown.Maximum and minimum TS, YM and E' were observed with PMMA and PU, respectively. Conversely, maximum and minimum Elong were associated with PU and PMMA, respectively. sIPN demonstrated intermediate mechanical properties which were dependent on the concentration of PMMA. Tan δ was similar for all sIPN. Increased Adv. and Rec. contact angles were associated with all sIPN compared to PU. Therefore, modifications of the mechanical properties of PU may be performed by the formation of PU/PMMA. The increased rigidity of sIPNs should be of clinical benefit in patients presenting with extrinsic compression of the ureter by providing increased resistance to compression and hence blockage. In addition, as it has been shown that increased encrustation on biomaterials occurs as the Adv. contact angle decreases the resistance of these sIPN to encrustation should at least be comparable, if not better, than PU.