Sexual dysfunction is a multifactorial problem with psychological, biological and social ramifications. As such, it is important to remember that, whatever the cause, treatment will require a holistic approach to achieve adequate resolution of the problem. Sexual dysfunction is a common unwanted effect of many different types of drug therapy. It is important for clinicians to be aware of this, as sexual problems are often difficult for many patients to talk about. This is especially so when the original problem is unrelated to sexual function. Many patients will suffer in silence unless the issue is discussed with them first.