The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
A series of anions derived from electrospray ionization of small oligonucleotides, each consisting of a single nucleobase (adenine, thymine, cytidine or guanine), have been subjected to ion trap tandem mass spectrometry. The data set allows for comparisons of dissociation behavior as functions of parent ion charge, oligomer length, and nucleobase identity. Parent ion charge is seen to play a major...
Multiply-charged cations derived from the positive ion electrospray of the oligonucleotide 5 -d(CTTAGCGCTAAG)-3 were subjected to reactions with the (M - CF 3 ) - and (M - F ) - anions derived from perfluoro-1,3-dimethylcyclohexane in a quadrupole ion trap. Both single strand ions and double strand ions formed from the self-complementary oligonucleotide were...
The effects of oligomer length, acceleration potential and nucleotide structure on the MALDI analysis of nucleic acids were examined. Increased oligomer size and decreased acceleration potential both increase oligomer residence time in the source region, resulting in an increase in observed fragmentation. Modified nucleosides which may be protonated but are resistant to fragmentation protect other...
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOFMS) was used to sequence modified oligonucelotides (MONs). Under delayed pulsed ion extraction conditions, sequence ions of MONs resulting from fragmentation within the ion source can be observed. In this work, several common types of antisense MONs with sizes up to 25-mer were studied including an oligodeoxynucleotide...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.