In the present report, we summarize our experience in the development of high-resolution position sensitive gas detectors for medicine and synchrotron radiation experiments at Budker Institute of Nuclear Physics for the last years. We have designed several versions of Multistrip Ionisation Chambers with a channel pitch varying from 0.4 down to 0.1mm. The high quantum efficiency (>65%) of these detectors allow its application in high quality diagnostic imaging. The detector with 0.1mm strip pitch and 20atm pressure of Xe demonstrates the best possible DQE and spatial resolution for gaseous detectors in a wide range of X-ray energies. Additionally, the initial results of feasibility study of the detector for beam position monitoring for Heavy Ion Therapy System are presented too.