Televideo bridges the gap between high need for behavioral services in rural and other underserved areas and limited access to professionals trained in evidence-based strategies such as cognitive-behavioral therapy (CBT). The authors first summarize the current literature concerning CBT using televideo, including therapeutic rapport as well as condition-specific considerations related to depressive symptoms and suicidality; anxiety and obsessive-compulsive disorders; eating disorders; alcohol and substance abuse; and behavioral medicine. They then address establishing and sustaining a televideo practice, including concerns related to clients/families, therapists, telemedicine site coordinators, and broader community participants. They conclude with a case example highlighting ethical considerations related to CBT services over televideo.