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In this study, we explore the effect of the lack of myelin on the diffusion characteristics and diffusion anisotropy obtained from high b-value q-space diffusion-weighted MRI (q-space DWI) in excised rat spinal cords. Twenty-one-day-old myelin-deficient (md) mutant (N=6) and control rats (N=6) were used in this study. The MRI protocol included multi-slice T 1 , T 2 , proton density...
Diffusion tensor echo planar magnetic resonance imaging of the inferior brain regions and the spinal cord suffers from tissue–air and tissue–bone interfaces, which cause severe susceptibility-induced artifacts. These artifacts consist of image distortions in the phase encode direction and also affect signal intensity. To correct for these distortions, we used the reversed gradient method. We find...
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