This study quantified the effects of lead stabilization by blending lead-containing sludge into glass-ceramics through sintering with aluminum- and silica-rich precursors. Using lead oxide (PbO) to simulate lead-laden sludge under thermal conditions, the predominant PbAl 2 O 4 phase was found at temperatures of 900–1000 °C while sintering with γ-Al 2 O 3 for 3 h. To analyze the influence of silica, amorphous SiO 2 and quartz were blended with γ-Al 2 O 3 for lead stabilization. The results revealed both silica precursors could crystallochemically incorporate lead into the PbAl 2 Si 2 O 8 structure, and the weight percentage of the PbAl 2 Si 2 O 8 phase ranged from 30% to 40% in the product after 3 h of sintering at 1000 °C. Furthermore, the calcined waterworks sludge was applied as a sintering precursor and found to result in 46 wt.% of PbAl 2 Si 2 O 8 in the sintered product, suggesting an effective and feasible waste-to-resource strategy for the beneficial use of waterworks sludge. Finally, a prolonged acid leaching experiment (lasting 23 d) evaluated the stability of lead in the PbAl 2 O 4 and PbAl 2 Si 2 O 8 phases. The concentration of lead in the PbAl 2 O 4 leachate was 30-times higher than that in the PbAl 2 Si 2 O 8 leachate at the end of the experiment, suggesting a preferred lead stabilization strategy of forming the PbAl 2 Si 2 O 8 phase.