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Optimized acceptor solutions, which eliminate electrolytically induced variations in their pH values, have been shown to improve electromembrane extraction (EME) performance. Acceptor solutions containing 500mM formic acid (pH 1.97) ensured stable EME process for three basic drugs extracted at 50V across 1-ethyl-2-nitrobenzene and constant extraction recoveries (66–89%) were achieved for 40–80min...
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