In many industrial applications, (CF3)2CFCN has been suggested as SF6 substitute, which possess a global warming potential (GWP100-yr) of 23500 relative to CO2. The temperature dependence of the rate coefficient (kOH) for the OH+(CF3)2CFCN reaction is reported for the first time: kOH(278–358K)=(5.9±3.2)×10−13exp{−(1856±162)/T}cm3 molecule−1s−1. A lifetime of 47years was estimated relative to that of CH3CCl3. Infrared absorption cross sections were also determined to derive the radiative efficiency (0.28Wm−2ppbv−1). A GWP100-yr of 3646 was estimated, resulting in a significant reduction of the contribution to global warming if SF6 was replaced by (CF3)2CFCN.