The nanosized Ag/Cu/HA powder is thermodynamically unstable and easily congregates during storing, which may make it lose the nanomaterial's properties. In this work, the performances of Ag/Cu/HA during storing were studied. The Ag/Cu/HA powders were prepared using a one-step co-precipitation method. The effects of storing on powder microstructures were investigated. The microstructures of Ag/Cu/HA powders were characterized by X-ray diffraction and scanning electron microscopy. The results show that the diffraction intensities and the sizes of the calcined Ag/Cu/HA powders are reduced during storing. Storing makes the diffraction angles of 002 and 300 peaks decreased and makes that of 211 peak increased. In addition, storing increases the crystal growth along the c-axis without the effect on the crystal morphology of powders. The stored Ag/Cu/HA powders can induce the formation of new HA crystal the same as the stored Ag/Cu/HA powders with platelet morphology and low intensity and crystallinity similar to nature bone.