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Lipopeptide MSI-843 consisting of the nonstandard amino acid ornithine (Oct–OOLLOOLOOL–NH 2 ) was designed with an objective towards generating non-lytic short antimicrobial peptides, which can have significant pharmaceutical applications. Octanoic acid was coupled to the N-terminus of the peptide to increase the overall hydrophobicity of the peptide. MSI-843 shows activity against bacteria...
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