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The ability of three sterols of different structure to influence the interaction of syringomycin E (an antifungal antibiotic that forms voltage dependent channels in planar lipid bilayers) with a planar lipid bilayer was evaluated. The rate of increase of bilayer conductance induced by syringomycin E was about 1000-times less in bilayers containing 50 mol% of cholesterol compared to bilayers without...
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