In 1998, a research on severe traumatic brain injury (TBI) patients in Lille conurbation 3 years after TBI highlighted many difficulties regarding autonomy and quality of family, social and professional lives. Lack of follow-up and infrastructures was clear. Since then, follow-up has organized itself around the TBI and Stroke 59/62 network and several specialized structures were created. The goals of the study were to compare people, their outcome and the accompaniment path between 1998 and 2015.All TBI people in the same geographic area were evaluated 3 years after TBI with the EBIS (European Brain Injury Society) document. Old data were compared to latest.On the situations analyzed respectively (33/29 patients), we observed fewer accidents on public roads (20/9), more domestic accidents (6/15), a decline in deaths (10/5) especially after neurosurgery (5/1). In 1998 and 2015 respectively, on the 23/24 evaluated patients, the overall autonomy tends to be more importance in 2015. About the family, the average score of quality of life has significantly improved (P=0.023). Changes in the role in the family (P=0.007) and the need for respite (P<10–3) are minor. Compared analysis of paths shows: 23/21 patients admitted in rehabilitation services. The average length of stay in rehabilitation decreased (166 vs. 118 days). Post-hospital orientation is more adapted: 0/6 in socio-medical specialized structures whereas 2/0 were admitted in psychiatry and 2/0 in geriatric long-stay. Among the 19/16 patients who have returned home, the multidisciplinary follow-up is more frequent: 0/14 by the multidisciplinary network mobile team and 0/5 by the socio-medical specialized services. Patients lost from sight are marginal (19/2). Access to specialized professionals has significantly increased for MPR doctors (5/19), psychologists and psychiatrists (9/18), social workers (4/18), occupational therapists (1/18), speech therapists (3/8) and physiotherapists (5/11).The evolution of hospital and post-hospital care has enabled a decrease in isolation, an improvement in autonomy and in family quality of life of persons with brain injury. However, some of them still escape from the follow-up. Unfortunately, follow-ups and resources remain unequal in France.