The dynamic recrystallization behavior in 42CrMo steel was investigated by hot compression tests. The effects of deformation temperature, strain rate, and initial austenite grain size on the dynamic recrystallization behavior were discussed. Based on the experimental results, the kinetic equations for the dynamic recrystallization behavior of 42CrMo steel were proposed. Results indicate that the effects of the deformation temperature, strain rate and initial austenitic grain size on the dynamic recrystallization behavior in 42CrMo are significant. The dynamic recrystallization in 42CrMo steel easily occurs at high deformation temperature, low strain rate and fine initial austenitic grain. A good agreement between the experimental and predicted results shows that the proposed kinetic equations can give an accurate estimate of the dynamic recrystallization behavior in hot deformed 42CrMo steel.