Brazilian Head and Neck Cancer Study Group1Participants in the Brazilian Head and Neck Cancer Study Group were as follows: Ricardo R. Brentani, Luiz P. Kowalski, José F. Soares, and Humberto Torloni (principal investigators, Ludwig Institute for Cancer Research and Hospital A. C. Camargo, São Paulo, Brazil); Raimunda N. Pereira (data processing, Hospital A. C. Camargo, São Paulo, Brazil); Mauro K. Ikeda, Roberto P. Andrade, Jose Magrin, Roberto E V Miguel, Carlos R. Santos, Leda M. B. Saba, Joao V. Salvajoli (Hospital A. C. Camargo, São Paulo, Brazil); Maria P. Curado, José C. Oliveira, Paula O. Montandon, Márcio M. Machado, Giovana F. Denofrio, Waldyr C. Quinta, Rene B. Alvarez, Rita C. G. Alencar (Hospital Araújo Jorge, Goiânia, Brazil); Alberto R. Ferraz, Lenine G. Brandão, Cláudio R. Cernea, Luiz R. M. Santos, Virgilius Araujo Filho, Avelino Antonangelo Filho, Joao L. F. Silva, Romualdo Della-Molle, Carlos V. Feriancic, Paulo C. Carneiro (Hospital das Clı́nicas–São Paulo University, São Paulo, Brazil); Benedito V. Oliveira, Gil Ramos, Lysandro S. Antunes (Hospital Erasto Gaertner, Curitiba, Brazil); Jozias Andrade Sobrinho, Abrão Rapoport, Marcos B. Carvalho, Antonio S. Fava, José F. Gois Filho, José F. S. Chagas, Jossi L. Kanda, Flavio M. Gripp, Marcelo H. Ribas, Ivan S. Castro (Hospital Heliópolis, São Paulo, Brazil); Joni M. S. Oliveira, José A. M. Oliveira, Ricardo C. Carvalho, Laércio B. Araújo (Hospital Napoleão Laureano, João Pessoa, Brazil); Paulo A. L. Pontes, Luiz C. Gregório, Márcio Abrahão, Onivaldo Cervantes, Marcos B. Paiva, Werner S. Hebbel, Reginaldo R. Fujita, Pedro H. H. Motta, Roberto A. Segreto (Hospital São Paulo–Escola Paulista de Medicina, São Paulo, Brazil); Nilton T. Herter, Neiro W. Mota, João G. Scholl, Ricardo G. Kroef, Paulo R. F. Godoy (Hospital Santa Rita, Porto Alegre, Brazil).
Background: Elective treatment of the neck in oral squamous cell carcinoma has changed over the last 20 years. The main object of this report is to present the results of a multi-institutional prospective study designed to compare standard treatment with modified radical classical neck dissection (MRND) to supraomohyoid neck dissection (SOH) in the management of the clinically negative neck in oral...