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Trypsin from bovine pancreas was modified by the polyaldehyde derivative of carboxymethylcellulose (CMC) via reductive alkylation with NaBH 4 . The modified enzyme contained 57% carbohydrate by weight, resulting from the modification of 52% of the amino groups of the protein. In comparison with the native protease, the modified trypsin retained 62% and 42% of the esterolytic and proteolytic...
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