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New aldehyde reductases (AR), ARII and ARIII, which reduce ethyl 4-chloro-3-oxobutanoate (4-COBE) to ethyl 4-chloro-3-hydroxybutanoate (CHBE), with NADPH as a cofactor, were purified from Sporobolomyces salmonicolor AKU4429. The two enzymes were different from another aldehyde reductase (ARI) which had already been purified and characterized [Yamada et al., FEMS Microbiol. Lett., 70 (1990) 45; Kataoka...
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