Mobile bearing (MB) total knee arthroplasty (TKA) was developed to provide low contact stress and unconstrained joint motion. We studied a consecutive series of 41 knees with mobile-bearing, posterior cruciate-retaining (CR) TKAs to determine if kinematics resembled normal knees or if kinematics changed over time. Patients were studied at 3 and 21 months average follow-up with weight-bearing radiographs at full extension, 30° flexion and maximum flexion. Shape-matching techniques were used to measure TKA kinematics. Implant hyperextension, maximum flexion and total ROM increased with follow-up. Tibial rotation and condylar translations did not change with time. The medial condyle did not translate from extension to 30°, but translated 5 mm anteriorly from 30° to maximum flexion. Lateral condylar translation was 3 mm posterior from extension to 30°, with no translation from 30° to maximum flexion. Tibiofemoral kinematics in CR-MB-TKAs were stable over time, but did not replicate motions observed in healthy knees. The mobile tibial insert showed rotation and translation at both follow-up examinations, but the patterns of translation were not predictable.